If the end of Week 16 is any sign, Week 17 could be quite the fruitful farewell for bettors. In a Monday Night Football showdown between the. ItÂ's called the line or spread and itÂ's known as betting Â'sides.Â' The common misconception is that Las Vegas sets the spread as its best guess at the margin. NFL Football Week 17 odds and betting lines. Includes updated point spreads, money lines and totals lines.